Endocrine Abstracts

Background: Patients with primary adrenal insufficiency (PAI) carry an increased risk of infections which can precipitate adrenal crises. They are thought to be more likely to contract COVID-19 and develop severe disease; however, little is known about the true impact of COVID-19 on these patients.Objectives: To assess the response of a large single-centre cohort of PAI patients to COVID-19, focusing on morbidity and health promotion attitudes.<p cla...

Introduction: Existing educational resources for polycystic ovary syndrome (PCOS) have limited inclusion of patient perspectives. We invited people with PCOS to share their lived experiences to understand their perception and opinion on the current standard of care.Methodology: Women aged 18-60 years with PCOS were invited to complete an online survey in April and May 2021. The survey had open questions focused on people’s lived experiences with PCO...

Background: As diagnostic workup and management of patients with Disorders of Sex Development (DSD) evolves, access to the latest advances should continue.Aims: To explore whether DSD patients in the West Midlands Region (WMR) remain under follow up, having optimal diagnostic workup and management.Method: An unselected cohort of 48 patients with discrepant phenotypic gender and sex chromosomes in the WMR were identified from the re...

Turner Syndrome (TS) affects 1:2500 females and is caused by the partial or complete loss of one X chromosome. About 80% of women with TS experience primary amenorrhea and therefore the only option for fertility treatment is ovum donation (OD). The remaining 20% may have the opportunity for a spontaneous pregnancy. Pregnancy in women with TS has been associated with excess obstetric risk such as miscarriage and hypertension. Maternal mortality has been estimated to be 2% risk ...

The 250 mg short synacthen test (SST) is the most commonly used tool to assess the integrity of hypothalamic-pituitary-adrenal (HPA) axis. There are many instances when compromise to HPA-axis function is potentially reversible (including the use of suppressive dose of prescribed glucocorticoids), but currently there are no data to guide clinicians as to the frequency of repeat testing or to the likelihood of HPA-axis recovery. We performed an observational, retrospective, anal...

Introduction: National Institute of Health and Care Excellence (NICE) recommends screening for emotional wellbeing as part of consultations for polycystic ovary syndrome (PCOS).Aim: We evaluated several dimensions of emotional wellbeing in people attending PCOS consultation in the UK and India.Methods: All people attending reproductive endocrine clinic for PCOS at three centres: Queen Elizabeth Hospital Birmingham, UK; Apollo Hospi...

Aim: To study differences in various aspects of emotional wellbeing among women with PCOS living in the UK and India.Methods: Women with PCOS were invited to complete an online survey between September and October 2020 in the UK and May and June 2021 in India. The survey included Hospital Anxiety and Depression Scale (HADS; score ≥11 cases of anxiety and depression, respectively), Body Image Concern Inventory (BICI; score ≥72 suggestive of bo...

Objective: This study investigated the association between ethnicity, birthplace and emotional and psychosexual wellbeing in women with Polycystic Ovary Syndrome (PCOS) in the community.Design: International cross-sectional study.Methods: Women with a self-reported PCOS diagnosis by a healthcare professional were invited to complete an online Blue Morpho questionnaire between September-October 2020 (UK) and May-June 2021 (India). F...

Background: Polycystic ovarian syndrome (PCOS) is a common endocrine disorder, with an estimated prevalence of 10-15% worldwide. PCOS can have adverse consequences on the emotional wellbeing of the patient. However, evidence exploring the relationship between PCOS and psychosexual wellbeing, specifically sexual function, and dysmorphic appearance concerns, is largely inconclusive.Aim: A systematic review and meta-analysis were undertaken to assess differ...

Introduction: With a global prevalence of around 10%, polycystic ovary syndrome (PCOS) is a common endocrine condition affecting women. Despite its prevalence, limited evidence exists around the condition and its impact on patients. Qualitative research provides insights into symptoms and experiences faced by women with PCOS that can affect management and compliance.Aim: A systematic review was undertaken to evaluate the current literature on ...